Peri-implantitis Biomarkers

We’re working to better understand and diagnose peri-implant disease through saliva and fluid biomarkers. Please refer suitable patients. They will receive specialist care, while helping us support research into earlier detection and understanding treatment outcomes.

What the study involves

Patients receive standard peri-implantitis treatment. We collect small samples of saliva, peri-implant fluid and plaque before treatment and 3, 6 and 12 months after treatment. All samples are stored for laboratory analysis, and participation is completely voluntary.

Who we're looking for

- Implants with bleeding on probing and/or suppuration
- Probing depth >6mm AND radiograph bone loss >3mm from the implant platform (all three critera required)

Please do not refer if the patient is

- A current smoker, or has uncontrolled diabetes (HbA1c >6.5%)
- Taking long-term immunosuppressants or anti-inflammatories
- Has an active infectious disease
Unsure if a case qualifies? Refer anyway, we can assess the patient's eligbility.

Referral process

Take a periapical radiograph if peri-implantitis is suspected, send a referral with medical history, implant history and current clinical findings.

What to tell your patients

- "The periodontist is researching ways to better detect and treat peri-implantitis early."
- "You'll get the same standard treatment, but will have some saliva and implant fluid for research collected. It's completely voluntary."

Benefits for your patient

Referred patients receive:
- Specialist care from a registered periodontist using the latest EFP guidelines
- Comprehensive monitoring at 3, 6 and 12 months

At a glance

1. Follow-up at 3, 6 & 12 months
2. Simple saliva & fluid sample collection
3. Voluntary - patients can withdraw anytime
4. Ethics approved by UQ
5. Helping detect peri-implant disease earlier

Ethics approved by UQ and registered ANZCTRACTRN12625000362493). Study team: Dr Su ShengQuach, Dr Pingping Han & Prof Saso Ivanovski.

Contact Us (Dr Su Sheng Quach):
sheng@bcpi.com.au
Referrals – https://www.bcpi.com.au/healthprofessionals/
patient-referral-form/

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